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BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) Peptide

BNIP3L Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937057

Aperçu rapide pour BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) Peptide (ABIN937057)

Antigène

BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

Origine

Mammifères

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of Bnip3 l antibody,
    Alternative Names: Bnip3l control peptide, Bnip3l antibody Blocking Peptide, Anti-Bnip3l Blocking Peptide, BCL2/adenovirus E1B interacting protein 3-like Blocking Peptide, C86132 Blocking Peptide, D14Ertd719e Blocking Peptide, Nip3L Blocking Peptide, Nix Blocking Peptide, Bnip3l, Bnipl-3, Bnipl 3, Bnipl-3 Blocking Peptide, Bnipl 3 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

    Sujet

    Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.

    Poids moléculaire

    24 kDa
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